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Kantarjian et al53 assessed the efficacy and protection of dasatinib, as in comparison with imatinib, for the initial-line remedy of CML-CP. 5 hundred and nineteen individuals with freshly diagnosed CML-CP have been randomly assigned to acquire dasatinib at a dose of one hundred mg as soon as each day (259 sufferers) or imatinib in a dose of 400 mg